Dr Meg Donovan
About
Dr Meg Donovan is a Research Officer at the Queensland Spatial Biology Centre (QSBC). Meg completed a Bachelor of Biomedical Science with Class I Honours at the University of Queensland (UQ) specialising in immunology and infectious diseases. She went on to complete her PhD at the UQ Frazer Institute, studying the host-pathogen interactions that occur during infection. In this time, Meg became interested in employing spatial biology technologies to answer biological questions about health and disease. At the QSBC, Meg is working on discovery and translational research projects using cutting-edge tissue profiling technologies to assess a multitude of biomarkers across every cell within cancer, heart, and lung disease.
Qualifications
Doctor of Philosophy in Immunology, The University of Queensland
Bachelor of Biomedical Science with Class I Honours, The University of Queensland
Featured Publications
ML Donovan, N Jhaveri, N Ma, BB Cheikh, J DeRosa, R Mihani, N Berrell, JY Suen, J Monkman, JF Fraser, A Kulasinghe. (2024). Protocol for high-plex, whole-slide imaging of human formalin-fixed paraffin-embedded tissue using PhenoCycler-Fusion. Cell Press STAR Protocols. doi: 10.1016/j.xpro.2024.103226
N Berrell, J Monkman, ML Donovan, T Blick, K O’Byrne, R Ladwa, CW Tan, A Kulasinghe. (2024). Spatially resolving the tumour microenvironment of head and neck cancer to discover novel predictive biomarkers of immunotherapy response. Immunology & Cell Biology. doi: 10.1111/imcb.12811
H Sadeghirad, J Monkman, N Liu, CW Tan, ML Donovan, A Moradi, J Yunis, C Perry, M Adams, K O’Byrne, M E. Warkiani, R Ladwa, B Hughes, A Kulasinghe. (2024). Transcriptomic and proteomic spatial profiling of tertiary lymphoid aggregates in head and neck cancer reveal spatial tissue dynamics and profiles associated with immunotherapy response. Journal of Translational Medicine. doi: 10.1186/s12967-024-05409-y
CW Tan, N Berrell, ML Donovan, J Monkman, H Sadeghirad, V Yaghoubi Naei, J Chen, A Rossenbloom, S Bonnett, M Conner, B Filanoski, C Kang, JM Beechem, C Barnett, R Ladwa, BGM Hughes, A Kulasinghe. The development of a high-plex spatial proteomic methodology for the characterisation of the head and neck tumour microenvironment. [PREPRINT] doi: 10.21203/rs.3.rs-5272207/v1
V Yaghoubi Naei, R Tubelleza, J Monkman, H Sadeghirad, ML Donovan, T Blick, A Wicher, S Bodbin, R Stad, S Basu, C Barnett, K O’Byrne, R Ladwa, M Ebrahimi Warkiani, BGM Hughes, A Kulasinghe. Spatial interaction mapping of PD-1/PD-L1 in Head and Neck Cancer reveals the role of Macrophage-Tumour Barriers associated with immunotherapy response. [PREPRINT] doi: 10.21203/rs.3.rs-5398442/v2
Professional Membership
2024 – Current – The American Association for Cancer Research (AACR), Associate Member
2017 – Current – The Australian and New Zealand Society for Immunology (ASI), Ordinary Membership Australia
Affiliations
2023 – 2026 – Adjunct Fellow, The University of Queensland, Frazer Institute
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