Research Theme
Coeliac Disease and Immune Health
Wesley Research Institute is developing a world leading multi-disciplinary research program for Coeliac Disease and Immune Health.
About this research theme
An estimated 1 in 70 Australians have Coeliac Disease which is caused when an intolerance to gluten in wheat, rye and barley products triggers an autoimmune response that attacks the small intestine. However, it is estimated that more than 80 per cent of all Australian coeliac sufferers remain undiagnosed.
If left untreated, coeliac disease is associated with a three-fold increase in the risk of autoimmune diseases, osteoporosis, and malignancy, decreased quality of life, and a two to four-fold increase in mortality.
The disease can also lead to juvenile tooth decay, malnutrition, depression, and infertility. Patients with coeliac disease can experience a wide range of symptoms such as abdominal pain, bloating, diarrhoea, constipation, fatigue and weight loss.
Coeliac Research Network
Coeliac Disease and Immune Health Research Objectives
Improve understanding
The Gluten Threshold Study is investigating whether there is an amount of gluten that coeliac patients can tolerate. The results will also help to influence food safety standards.
Creating communities
Through the new Coeliac Research Network, we hope to bring patients, clinicians and scientists together to really progress the multi-disciplinary research program.