This project aims to find new biomarkers for immunotherapy in patients with melanoma.

Research Objectives

Status

Current

Recruitment

Open

Patient Group

Cancer – Stage IV Melanoma

Study location

Wesley Research Insitute, The Wesley Hospital

Study type

Investigator Initiated

Finding new biomarkers for immunotherapy in patients with melanoma

    Lead investigator    
            Private: Dr Agnieszka Malczewski        

        Clinical trial coordinator		
				Venita Bali			

Technical title

Metabolomics in Enhancing Responses to Cancer ImmunoTherapy in Melanoma (MERIT-M)

About this research project

Cancer immunotherapy has been shown to provide patients with an excellent new type of treatment and is in common use world-wide. Unfortunately, we know that not all patients will respond to their immunotherapy treatment in the same way.

Responses to immunotherapy may be affected by a patient’s microbiome, or the community of bacteria that live in their bowel. This group of bacteria can influence the immune system by increasing or decreasing certain types of white cells, called T cells that are produced in the body. By analysing the bacteria, this project aims to find new biomarkers for immunotherapy in patients with melanoma.

Latest News

From diagnosis to clinical trials: Aidan’s Coeliac Disease journey

An estimated 1 in 70 Australians have coeliac disease, with more than 80 per cent of all Australian coeliac disease sufferers remain undiagnosed. Aidan, a coeliac disease clinical trial participant at Wesley Research Institute, was part of that statistic remaining undiagnosed for a lengthy period of time despite experiencing symptoms.

Going Gluten Free – Pratical Tips for Coeliac Disease Management

Living with coeliac disease requires significant lifestyle changes. At Wesley Research Institute, we understand how overwhelming this journey can feel, whether you are newly diagnosed or supporting a loved one. In this article, we’ll share practical, research-backed tips to help both coeliac patients and their support networks navigate this transition with confidence.

Research Advisory Board

We welcome Dr John Rivers, Professor Janet Hardy, Professor Jennifer Byrne, Professor John Prins, Professor Steven Lane, Professor Cathy Mihalopoulos and Professor Jill Francis to our newly established Research Advisory Board.

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